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HLA class II genes

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Research Progress on Correlation between HLA and SLE Pathogenesis

Systemic lupus erythematosus (SLE) is an inflammatory connective tissue dermatosis mediated by autoimmunity. It is characterized by the production of a variety of autoantibodies. The study of the pathogenesis of SLE mainly involves genetic, immune and environmental factors. The human leukocyte anti-gen (HLA) system is currently the most complex polymorphic system known to the human body. Since the first HLA …

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